Table 1 Demographics of responders and nonresponders to screening invitation

Age at randomisation (SD)

58.9 (5.66)

59.1 (5.47)

< 0.0001^a

N

100,953

90,285

Mean England Index of Multiple Deprivation (IMD) score (SD)

25.04 (17.74)

20.66 (15.49)

< 0.0001^a

N

85,521

78,882

Mean Wales Index of Multiple Deprivation (IMD) score (SD)

22.27 (15.28)

19.04 (14.08)

< 0.0001^a

N

15,432

11,418

 England and Wales combined % OR (95 % CI)

87 % (baseline)

85 %

< 0.0001^c

0.84 (0.82–0.86)

 England % (OR; 95 % CI)

86 % (baseline)

84 % (0.85; 0.83–0.87)

< 0.0001^c

 [adjusted OR; 95 % CI; p value]^b

[1.04; 0.99–1.09]

[0.14]^c

 Wales % (OR; 95 % CI)

95 % (baseline)

95 % (1.01; 0.91–1.13)

0.83

 [adjusted OR; 95 % CI; p value]^b

[1.11; 0.95–1.30]

[0.19]^c