European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): study protocol for a randomized controlled, non-inferiority trial in eight European countries

Table 2 Overview of measures

Variable	Instrument	Screening Baseline	3 months	6 months	12 months
Questions taken from patients
Demographics		X
Current treatment		X
Diagnostic interview	M.I.N.I.	X			X
Depressive symptoms	PHQ-9 and QIDS-SR16	X	X	X	X
Quality of life	EQ-5D-5L	X	X	X	X
Societal costs	TIC-P	X	X	X	X
Treatment preference		X
Patient expectancy	CEQ	X
Working alliance	WAI-SF		X^c
Technology alliance	TAI-OT^a		X^c
Client satisfaction	CSQ		X^c
Satisfaction with the online program	SUS^a		X^c
Questions taken from therapists
Working alliance	WAI-SF		X^c
Satisfaction with the online program	SUS^a,b		X^c

^aOffered to condition receiving blended treatment only
^bHas to be completed once per therapist after completion of the first treatment
^cQuestionnaires may be taken at 6 months when the duration of treatment is longer than 3 months
CEQ Credibility and Expectancy Questionnaire, CSQ Client Satisfaction Questionnaire-8, EQ-5D-5L EuroQol 5 dimensions 5 levels, M.I.N.I. MINI International Neuropsychiatric Interview, PHQ-9 Patient Health Questionnaire-9, QIDS-SR16 Quick Inventory of Depressive Symptomatology, SUS System Usability Scale, TAI-OT Technology Alliance Inventory-Online Therapy, TIC-P Trimbos and iMTA Questionnaires on Costs Associated with Psychiatric Illness, WAI-SF Work Alliance Inventory short form

ISSN: 1745-6215