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Table 1 Hypothesized rates of primary outcome of death or moderate or severe impairment at 18–22 months: these rates were used for sample size calculation

From: Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial

 

Depth of cooling

 
 

33.5 °C

32.0 °C

Margin

Duration of cooling

 72 h

45 %

30 %

37.5 %

 120 h

30 %

25 %

27.5 %

Margin

37.5 %

27.5 %

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