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Table 1 Hypothesized rates of primary outcome of death or moderate or severe impairment at 18–22 months: these rates were used for sample size calculation

From: Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial

  Depth of cooling  
  33.5 °C 32.0 °C Margin
Duration of cooling
 72 h 45 % 30 % 37.5 %
 120 h 30 % 25 % 27.5 %
Margin 37.5 % 27.5 %