Table 4 Predicted probabilities for any exploration of subgroup analysis and for reporting subgroup analysis using appropriate methods
Condition | Predicted probability (any subgroup analysis) | Predicted probability (subgroup analysis using appropriate methods) |
|---|---|---|
Journal of publication | Â | Â |
 British Medical Journal | 0.55 (0.41, 0.69) | 0.52 (0.33, 0.71) |
 Annals | 0.57 (0.42, 0.73) | 0.84 (0.63, 1.05) |
 Journal of the American Medical Association | 0.60 (0.49, 0.70) | 0.70 (0.55, 0.86) |
 Lancet | 0.60 (0.53, 0.68) | 0.76 (0.67, 0.85) |
 New England Journal of Medicine | 0.66 (0.59, 0.73) | 0.67 (0.59, 0.75) |
Year of publication | Â | Â |
 2007 | 0.61 (0.54, 0.69) | 0.77 (0.68, 0.87) |
 2010 | 0.57 (0.50, 0.64) | 0.71 (0.61, 0.80) |
 2013–2014 | 0.66 (0.59, 0.72) | 0.65 (0.57, 0.73) |
Biostatistician as coauthor | Â | Â |
 No biostatistician as coauthor | 0.61 (0.55, 0.68) | 0.65 (0.56, 0.74) |
 Biostatistician as coauthor | 0.61 (0.56, 0.70) | 0.73 (0.67, 0.80) |
Medical condition under study | Â | Â |
 Obstetrics/gynecological | 0.43 (0.25, 0.61) | 0.71 (0.42, 1.00) |
 Cardiovascular | 0.61 (0.52, 0.70) | 0.85 (0.75, 0.95) |
Infectious disease | 0.57 (0.46, 0.69) | 0.58 (0.44, 0.73) |
 Cancer | 0.68 (0.57, 0.78) | 0.56 (0.41, 0.70) |
 Psychiatry/neurology | 0.64 (0.51, 0.77) | 0.54 (0.32, 0.76) |
 Autoimmune, including DM | 0.69 (0.57, 0.82) | 0.67 (0.46, 0.87) |
 Pulmonary/critical care | 0.50 (0.32, 0.68) | 0.83 (0.64, 1.00) |
 Other chronic disease | 0.75 (0.65, 0.85) | 0.79 (0.64, 0.95) |
 Other, uncategorized | 0.48 (0.33, 0.64) | 0.89 (0.68, 1.00) |
First author’s region |  |  |
 Other | 0.56 (0.44, 0.69) | 0.63 (0.48, 0.78) |
 North America | 0.63 (0.57, 0.69) | 0.70 (0.61, 0.79) |
 Europe | 0.62 (0.55, 0.68) | 0.73 (0.65, 0.81) |
Funding | Â | Â |
 No industry funding | 0.56 (0.51, 0.62) | 0.78 (0.71, 0.85) |
 Industry funding | 0.69 (0.62, 0.75) | 0.62 (0.54, 0.69) |
Significance of the primary outcome | Â | Â |
 Not significant | 0.68 (0.62, 0.75) | 0.75 (0.66, 0.84) |
 Significant | 0.58 (0.52, 0.63) | 0.67 (0.61, 0.74) |
Sample size | Â | Â |
 Quintile 1 | 0.28 (0.17, 0.38) | 0.51 (0.27, 0.75) |
 Quintile 2 | 0.54 (0.44, 0.63) | 0.70 (0.56, 0.84) |
 Quintile 3 | 0.67 (0.57, 0.77) | 0.70 (0.58, 0.81) |
 Quintile 4 | 0.72 (0.63, 0.82) | 0.75 (0.66, 0.84) |
 Quintile 5 | 0.85 (0.78, 0.93) | 0.72 (0.62, 0.82) |