How can we optimise inhaled beta2 agonist dose as ‘reliever’ medicine for wheezy pre-school children? Study protocol for a randomised controlled trial

Table 2 Schedule of assessments

Schedule items	Enrolment	Randomisation	Baseline	Testing: Dose 1	Testing: Dose 2
Time point				T₀	T_{45 min}
Enrolment
Eligibility screening	X
Informed consent/assent	X
Allocation		X
Interventions
Dose 1				X
Dose 2					X
Assessments
Clinical history	X
Recent relevant medications	X
Adverse events				X	X
Saliva sample (for DNA work)			X
Rint assessment			X	X	X
Urine sampling				X	X

ISSN: 1745-6215