Skip to main content

Table 3 Nutritional deficiencies and their management strategies prior to entering the intervention trial

From: Vitamin D and omega-3 fatty acid supplements in children with autism spectrum disorder: a study protocol for a factorial randomised, double-blind, placebo-controlled trial

Nutritional deficiency

Management

Vitamin D

Participants with serum 25(OH)D concentrations <25 nmol/L will be offered supplementation of 400 IU per daya

Iron

Children with iron deficiency will be offered iron supplements and postponed entry into the trial after 3 months. Children will not be retested A child will be iron deficient when two of the following pools are abnormal: red cell pool (haemoglobin <111 g/L, red blood cell distribution width >14 %), transport iron (iron saturation <16 %) and/or storage iron (serum ferritin ≤15 μg/L)a. Criteria for treatment will be according to the New Zealand Ministry of Health guidelinesb

Vitamin B12

Children with serum levels <110 pmol/L will be offered the option of prescribed supplements or dietary advice to improve status

  1. aNew Zealand Ministry of Health 2015 [83]
  2. bRetrieved from https://www.starship.org.nz/for-health-professionals/starship-clinical-guidelines/i/iron-deficiency/on 5 March 2015