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Table 1 Summary of study characteristics

From: Identifying the participant characteristics that predict recruitment and retention of participants to randomised controlled trials involving children: a systematic review

Author

Year

Intervention

Study Length

Study Design

Focus

Country

Sample Size

Setting

Disease Type

Medical or non medical intervention

Target Population

Aylward GP, Hatcher RP, Stripp B, Gustafson NF and Leavitt LA (1985) [22]

1985

Dexamethasone administration

Repeated visits

RCT individual

Retention

USA

645

Health setting - university centres

Prevention of respiratory distress syndrome

Medical

Babies - surviving infants

Baker CN, Arnold DH and Meagher S (2011) [23]

2011

Parenting intervention

8 weeks

RCT cluster

Recruitment

USA

106

Community - childcare centres

Parent training for preventing conduct problems

Non medical

Families of preschoolers mean age of child 4.6 years (intervention group only)

Boggs SR, Eyberg SM, Edwards DL, Rayfield A, Jacobs J, Bagner D and Hood KK (2004) [24]

2004

Parent child interaction therapy (PCIT)

Longitudinal - time unlimited, mean treatment length 13 weekly sessions

RCT individual

Retention

USA

46/61 enrolled

Unclear

Existing disruptive behaviour

Medical

Children with disruptive behaviour disorders

Byrnes HF, Miller B A, Aalborg AE and Keagy CD (2012) [25]

2012

Parenting intervention

Longitudinal but this looks at enrolment

RCT individual

Recruitment

USA

351/744 eligible

Health setting - medical centres

Substance use prevention

Non medical

Families with an 11-12 year old

Constantine WL, Haynes CW, Spiker D, Kendall-Tackett K and Constantine NA (1993) [26]

1993

3 year home visits, parent support groups and education program v normal care

3 years

RCT individual

Retention

USA

885/1302 eligible

Mixed - large urban tertiary care centres and satellite clinics for hard to reach

Low birth weight premature infants reducing health and development problems

Non medical

Babies born before 37 weeks

Cunningham CE, Boyle M, Offord D, Racine Y, Hundert J, Secord M and McDonald J (2000) [28]

2000

Parenting intervention

Enrolment

RCT cluster

Recruitment (retention not clear)

Canada

1498

Community - schools

Children at risk of disruptive behaviour disorder - parent training

Non medical

5-8 year olds with high parent reported externalising problems

Cunningham CE, Bremner R and Boyle M (1995) [27]

1995

Parenting intervention

Longitudinal

RCT individual

Retention

Canada

150

Community - community-based neighbourhood schools and community centres

Children at risk of disruptive behaviour disorder - parent training

Non medical

Junior kindergarten school children with problems at home

Damashek A, Doughty D, Ware L and Silovsky J (2011) [29]

2011

Parenting intervention

Longitudinal

RCT individual

Recruitment

USA

398

Community - home

Child maltreatment prevention

Non medical

Female caregivers with a child 1-5 years in home

Daniels LA, Wilson JL, Mallan KM, Mihrshahi S, Perry R, Nicholson JM and Magarey A [30]

2012

Parenting intervention

Longitudinal

RCT individual

Recruitment and retention

Australia

698

Community - community child health clinics

Nutrition – prevention

Non medical

1st time mothers of healthy infants

Eisner M and Meidert U (2011) [31]

2011

Parenting intervention

Longitudinal but this looks at enrolment

RCT cluster

Recruitment (retention not clear)

Switzerland

821 test group only

Community - public primary schools

Parent training (triple P)

Non medical

Children in primary school

Fernandez MA and Eyberg SM (2009) [32]

2009

PCIT

2 year follow up

RCT individual

Retention

USA

99

Health setting - PCIT Lab

Existing disruptive behaviour

Medical

3-6 year olds with Disruptive Behaviour Disorder

Firestone P and Witt JE (1982) [33]

1982

Parenting intervention

4 month programme

RCT crossover

Retention

Canada

83 families (test group only)

Health setting - psychology department hospital

Hyperactive children

Medical

Families of hyperactive children 5-9 years of age

Gross D, Julion W and Fogg L (2001) [34]

2001

Parenting intervention

1 year - 15 months

RCT cluster

Recruitment and retention

USA

155 test group only

Community - childcare centres (community bases)

Parent training

Non medical

2-3 year olds attending day care centres, serving low income families

Heinrichs N, Bertram H, Kuschel A and Hahlweg K (2005) [35]

2005

Parenting intervention

Enrolment

RCT cluster

Recruitment

Germany

186/282 enrolled, test group only

Community - schools

Prevention of emotional and behaviour problems, parent training

Non medical

3-6 year olds

Ireys HT, DeVet KA, and Chernoff R (2001) [36]

2001

Parenting intervention

15 months

RCT individual

Recruitment

USA

161

Mixed - pediatric practices and home visits

Children at risk of mental health problems because of serious ongoing physical health conditions

Medical

Mothers with children aged 7-10 months with diabetes sickle cell disease, cystic fibrosis or asthma

Katz KS, El-Mohandes PA, Johnson DM, Jarrett PM, Rose A and Cober M (2001) [37]

2001

Parenting intervention

12 months

RCT individual

Recruitment and retention

USA

286

Community - Home visits

Parenting intervention to increase use of healthcare and to increase skills in providing safe and structured child rearing

Non medical

Mothers of babies, low income

Mihrshahi S, Vukasin N, Forbes S, Wainwright C, Krause W, Ampon R, Mellis C, Marks G, Peat J (2002) [39]

2002

Parenting intervention

5 years

RCT individual

Recruitment

Australia

616

Community - home visits

Asthma – prevention

Medical

Pregnant women with asthma or father has asthma

Miller GE and Prinz RJ (2003) [40]

2003

Parenting intervention

Longitudinal

RCT individual

Retention

USA

147

Health setting - children and family centre affiliated with a university

Serious childhood aggression and conduct problems

Medical

Families with 5-9 year old boys

Moser DK, Dracup K and Doering JV (2000) [41]

2000

3 methods of cardiopulmonary resuscitation training v control

Longitudinal

RCT individual

Retention

USA

578

Unclear

Cardiac/respiratory arrest

Medical

Parents and caregivers of high risk neonates at risk of cardiac/respiratory arrest

Multicentre Otitis Media Study Group (2001) [38]

2001

Bilateral intervention tubes with and without adenoidectomy against non surgical management

12 weeks from 1st visit to randomisation

RCT individual

Recruitment

UK

1315

Health setting - 3 UK Centres - Hospitals

Otologica (hearing) Glue Ear

Medical

3y3m - 9y9m referred for otological problems (OME)

Ramos-Gomez F, Chung LH, Beristain RG, Santo W, Jue B, Weintraub J, Gansky S (2008) [42]

2008

Dental disease management

Longitudinal

RCT individual

Recruitment and retention

USA

361

Health setting - health centres

Childhood caries

Non medical

Pregnant women attending community health centres, mostly Hispanic

Roggman LA, Cook GA, Peterson CA and Raikes HH (2008) [43]

2008

Parenting intervention

Longitudinal

RCT individual

Retention

USA

564 test group only

Community - interviews by phone and home visits

Home visits for early childhood development

Non medical

Children up to age 3

Van den Akker EH, Rovers MM, Van Staaij BK, Hoes AW and Schilder AGM (2003) [44]

2003

Adenotonsillectomy

Enrolment

RCT individual

Recruitment

Netherlands

First 270 randomised children

Health setting - hospital

Adenotonsille- ctomy

Medical

2-8 years old

Vermaire JH, van Loveren C and Hoogstraten J (2011) [49]

2011

Caries prevention strategies - detail unknown

6 years

RCT individual

Recruitment

Netherlands

286

Health setting - dental practices

Caries

Non medical

6 year old in dental clinics

Wagner M, Spiker D, Inman Linn M and Hernandez F (2003) [45]

2003

Parenting intervention

Monthly home visits, look at sample up to child's first birthday

RCT individual

Retention

Canada

238

Community - home based

Behaviour

Non medical

Low income families, up to 8 months old (home visitation group only - not control)

Werba BE, Eyberg SM, Boggs SR and Algina J (2006) [46]

2006

PCIT

Longitudinal

RCT individual

Retention

USA

99

Health setting - psychology clinic in health sciences centre

Existing disruptive behaviour disorder – PCIT

Medical

Families of 3-6 year olds

Winslow EB, Bonds D, Wolchik S, Sandler I, Braver S (2009) [47]

2009

Parenting intervention

11 weeks

RCT individual

Recruitment and retention

USA

325

Mixed - home and sessions on University campus

Parenting programs for divorced mothers

Non medical

Divorced mothers with a child aged 9-12

Zebracki K, Drotar D, Kirchner H, Schluchter M, Redline S, Kercsmar C and Walders N (2003)[48]

2003

Control v session of problem solving therapy for family asthma management skills

Longitudinal

RCT individual

Recruitment and retention

USA

327

Health setting - teaching hospital

Asthma

Medical

4-12 year olds

  1. RCT randomised controlled trial, SES socioeconomic status