Fig. 2

World map illustrating the distribution of recruiting sites for all included studies, inspired by the World Health Organization (WHO) regional classification. Figures within each country indicate only one trial [27] had a recruiting site in South Africa and so this was combined with countries in the WHO Eastern Mediterranean region to create the Middle East and Africa region (n = 20). The WHO Region of the Americas was separated into North and South America because we anticipated that language differences might influence choice of outcome instruments. Similarly, Australia and New Zealand were considered separately from Western Pacific region, as Oceania, while other countries were combined with the WHO Southeast Asia region to create a single Asian region