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Table 8 Severity of grading and use of normal and abnormal laboratory values

From: TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial

  Grade 1 Grade 2 Grade 3 Grade 4
Hemoglobin 8.5–10.0 g/dL 7.5–8.4 g/dL 6.5–7.4 g/dL <6.5 g/dL
Absolute neutrophil count 1000–1300/mm3 750–999/mm3 500–749/mm3 <500/mm3
Platelets 100,000–124,999/mm3 50,000–99,999/mm3 25,000–49,999/mm3 <25,000/mm3
Creatinine 1.1–1.3 × ULN 1.4–1.8 × ULN 1.9–3.4 × ULN ≥3.5 × ULN
Alanine aminotransferase 1.25–2.5 × ULN 2.6–5.0 × ULN 5.1–10.0 × ULN >10.0 × ULN
  1. ULN upper limit of normal