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Table 7 Antimalarial efficacy flow chart

From: TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial

Days after malaria diagnosis →

0

1

2

3

7

14

21

28

Unscheduled visit (before d28)

Procedure ↓

Clinical Assessment

C

C

C

C

C

C

C

C

C

Temperature

C

C

C

C

C

C

C

C

C

Questioning about antimalarial drug use

C

C

C

C

C

C

C

C

C

Finger stick blood sample for malaria smear

C

R

R

R

R

R

R

R

C

Finger stick blood sample for filter paper sample for PCR analysis

R

R

R

R

R

R

R

R

R

Administration of antimalarial drug (per Malawi Ministry of Health Protocol)

C

C

C

      
  1. C= procedures that are part of clinical care
  2. R= research procedures