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Fig. 2 | Trials

Fig. 2

From: Design of trials for interrupting the transmission of endemic pathogens

Fig. 2

Example single random SWCRT sequence runs of the transmission simulator. Incidence of clinical events in intervened (red) and non-intervened (blue) populations as modeled by the transmission simulator for three levels of community radius, a 0.5 km, b 1.0 km, and c 1.5 km. The cluster width is held constant at 1 km, corresponding to an area of 1 km2. The transmission model input efficacy is 80 %. During the first 40 time steps of each simulation, the incidence of clinical events is an auto-regressive moving average process that oscillates around the initial incidence value of 20 %. The intervention commences at time step 41 and from time steps 41 to 121, the incidence of the pathogen decreases sharply in both arms due to the direct effect of the intervention and the community effect. The community effect has more impact at greater radii. SWCRT stepped wedge cluster randomized trial

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