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Table 3 Effect of tranexamic acid (TXA) on death or hysterectomy by subgroups

From: The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial

Subgroup

TXA

Placebo

Risk ratio (99 % CI)

 

Death or hysterectomy

Received TXA

Death or hysterectomy

Received Placebo

 

Time between delivery and randomisation:

     

 ≤ 1 h

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 1–3 h

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 > 3 h

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 (p = 0.XXX)*

     

Type of delivery:

     

 Vaginal

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 Caesarean section

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 (p = 0.XXX)

     

Primary cause of haemorrhage:

     

 Uterine atony

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 Other/unknown

NN (X %)

N NNN

NN (X %)

N NNN

X.XX (X.XX–X.XX)

 (p = 0.XXX)

     
  1. Notes
  2. *p values from unadjusted tests of interaction in a logistic regression model to assess evidence for whether the effect of treatment differs across subgroup categories