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Table 1 Baseline characteristics by arm, BIS Phase IIInm - patients with non-malignant conditions

From: The clinical and cost effectiveness of a Breathlessness Intervention Service for patients with advanced non-malignant disease and their informal carers: mixed findings of a mixed method randomised controlled trial

Baseline characteristics - patients

Mean (SD) or % (n)

Intervention arm (fast track)

Control arm (waiting list)

Total

Age (years)

72.3 (10.6)

72.2 (9.4)

72.2 (9.9)

Sex (male)

64 % (28)

58 % (25)

61 % (53)

Lives alone

21 % (9)

37 % (16)

29 % (25)

Diagnosis:

   

 COPD

 Other non-malignant

80 % (35)

20 % (9)

88 % (38)

12 % (5)

83 % (72)

17 % (14)

GOLD COPD classification (if available):

   

 1 - mild

 2 - moderate

 3 - severe

 4 - very severe

9 % (2)

9 % (2)

48 % (11)

35 % (8)

(23/35 with COPD)

0 % (0)

32 % (7)

36 % (8)

32 % (7)

(22/38 with COPD)

5 % (2)

20 % (9)

42 % (19)

33 % (15)

(45/72 with COPD)

Charlson Co-Morbidity Index (0-9)a

4.4 (1.39)

4.4 (1.46)

4.4 (1.42)

Australia-modified Karnofsky Performance Scale (0-100)b,c

66.8 (14.9)

65.8 (14.9)

66.3 (14.9)

Modified Borg at rest (0-10)a

1.9 (1.27)

1.9 (1.05)

1.9 (1.16)

Modified Borg on exertion (0-10)a

6.5 (2.28)

6.0 (2.18)

6.2 (2.23)

NRS worst breathlessness 24 h (0-10)a

6.0 (2.14)

5.6 (2.29)

5.8 (2.21)

NRS breathlessness now (0-10)a

2.8 (2.13)

2.8 (1.91)

2.8 (2.01)

NRS average breathlessness 24 h (0-10)a

4.5 (1.99)

4.7 (1.83)

4.6 (1.91)

NRS distress due to breathlessness (0-10)a

6.2 (2.50)

5.9 (3.17)

6.0 (2.84)

Anxiety score (HADS; 0-21)a

7.84 (3.79)

8.86 (4.75)

8.35 (4.31)

Depression score (HADS; 0-21)a

6.81 (3.27)

7.84 (3.72)

7.33 (3.52)

Anxiety (HADS)a:

   

 Normal (0-7)

 Mild (8-10) = possible clinical disorder

 Moderate (11-14) = probable clinical disorder

 Severe (15-21) = probable clinical disorder

42 % (18)

35 % (15)

18 % (8)

5 % (2)

51 % (22)

9 % (4)

26 % (11)

14 % (6)

47 % (40)

22 % (19)

22 % (19)

9 % (8)

Depression (HADS)a:

   

 Normal (0-7)

 Mild (8-10) = possible clinical disorder

 Moderate (11-14) = probable clinical disorder

 Severe (15-21) = probable clinical disorder

58 % (25)

28 % (12)

12 % (5)

2 % (1)

51 % (22)

17 % (7)

30 % (13)

2 % (1)

55 % (47)

22 % (19)

21 % (18)

2 % (2)

CRQ dyspnoea score (1-7)b

3.12 (0.91)

3.06 (0.92)

3.09 (0.91)

CRQ fatigue score (1-7)b

3.15 (0.96)

2.76 (1.18)

2.95 (1.09)

CRQ emotional function score (1-7)b

3.95 (1.05)

3.78 (1.18)

3.86 (1.12)

CRQ mastery score (1-7)b

3.87 (1.28)

3.91 (1.34)

3.89 (1.30)

Number of respondents

37-44

37-43

74-87

  1. aHigh score is worse
  2. bHigh score is better
  3. cA score of 60 represents ’Requires occasional assistance but is able to care for most of needs’