From: CAMERA2 – combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial
GFR
Daptomycin dose
>50 ml/min
6–10 mg/kg IVI q24h
11–50 ml/min
6–8 mg/kg q24h IVI
≤10 but not on haemodialysis
8 mg/kg q48h IVI
On continuous renal replacement therapy
On haemodialysis
8 mg/kg q48h IVI, dose after dialysis