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Table 3 Adjustment of (flu)cloxacillin doses according to renal function

From: CAMERA2 – combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial

GFR

Flucloxacillin dose

Cloxacillin dose

>50 ml/min

2 g q6h IVI

2 g q6h IVI

11–50 ml/min

2 g q6h IVI

2 g q6h IVI

≤10 but not on haemodialysis

1 g q8h IVI

2 g q6h IVI

On continuous renal replacement therapy

2 g q6h IVI

2 g q6h IVI

On haemodialysis

Not for flucloxacillin (cefazolin 2 g 3x/week)

Not for cloxacillin (cefazolin 2 g 3x/week)