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CAMERA2 – combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial

  • Steven Y. C. Tong1, 2,
  • Jane Nelson1,
  • David L. Paterson3,
  • Vance G. FowlerJr4, 5,
  • Benjamin P. Howden6,
  • Allen C. Cheng7, 8,
  • Mark Chatfield1,
  • Jeffrey Lipman9, 10,
  • Sebastian Van Hal11,
  • Matthew O’Sullivan12, 13,
  • James O. Robinson14, 15,
  • Dafna Yahav16, 17,
  • David Lye18, 19,
  • Joshua S. Davis1, 20Email authorView ORCID ID profile and
  • for the CAMERA2 study group and the Australasian Society for Infectious Diseases Clinical Research Network

Received: 27 October 2015

Accepted: 17 March 2016

Published: 31 March 2016

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
27 Oct 2015 Submitted Original manuscript
14 Mar 2016 Author responded Author comments - Steven Tong
Resubmission - Version 2
14 Mar 2016 Submitted Manuscript version 2
17 Mar 2016 Editorially accepted
31 Mar 2016 Article published 10.1186/s13063-016-1295-3

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Menzies School of Health Research, Charles Darwin University, Darwin, Australia
Royal Darwin Hospital, Darwin, Australia
University of Queensland, Centre for Clinical Research, Herston, Australia
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, USA
Duke Clinical Research Institute, Duke University Medical Center, Durham, USA
Microbiological Diagnostic Unit Public Health Laboratory, The University of Melbourne, at The Doherty Institute, Melbourne, Australia
Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Australia
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Burns, Trauma Critical Care Research Centre, The University of Queensland, Brisbane, Australia
Faculty of Health, Queensland University of Technology, Brisbane, Australia
Department of Microbiology and Infectious Disease Royal Prince Alfred Hospital, Sydney, Australia
Centre for Infectious Diseases and Microbiology, Westmead Hospital, Sydney, Australia
Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney, Australia
Department of Microbiology and Infectious Diseases, Pathwest Laboratory Medicine WA, Royal Perth Hospital and Fiona Stanley Hospital, Perth, Australia
Australian Collaborating Centre for Enterococcus and Staphylococcus Species (ACCESS) Typing and Research, School of Veterinary and Life Sciences, Murdoch University, Perth, Australia
Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel
Rabin Medical Center, Petah Tikvah, Israel
Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
John Hunter Hospital, Newcastle, Australia