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Primary outcomes
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HIV viral load (chart-abstracted HIV RNA)
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Undetectable viral load (binary) (primary) Log change in viral load from baseline (continuous)
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Dose-taking adherence (MEMS)
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Took at least 85 % of prescribed doses (binary) (primary) Percentage of prescribed doses taken (continuous)
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Secondary outcomes
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Dose-timing adherence (MEMS)
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Percentage of prescribed doses taken in correct time window (±2 h for twice-daily regimens and ±3 h for once-daily regimens) (continuous) Took at least 85 % of prescribed doses on time (binary)
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Dose-taking adherence (self-report)
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Percentage of prescribed doses taken in past 7 days (continuous) Took at least 85 % of prescribed doses (binary) Visual analogue scale rating from 0 % to 100 % adherence over past 30 days
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Dose interruptions (MEMS data)
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Number of >48-h interruptions
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Clinic attendance (chart abstract; self-report)
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Number of attended and missed clinic appointments in past 6 months
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CD4 count (chart-abstracted)
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Change from baseline
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