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Table 2 Number of ADs (95 % CI) per 10,000 registered trials per time period

From: Adaptive designs undertaken in clinical research: a review of registered clinical trials

Year Total number Total number of Number of ADs per 10,000
  of ADs registered trials registered trials (95 % CI)
2001–2005 10 9502 11 (4, 17)
2006–2008 37 17,116 22 (15, 29)
2009–2011 50 17,097 29 (21, 37)
2012–2013 a 46 11,037 38 (27, 50)
  1. AD adaptive design, CI confidence interval
  2. aResults from 2014 excluded as this was only a partial year