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Table 2 Protocol characteristics of academic clinical drug trials by type of study, continued

From: From protocol to published report: a study of consistency in the reporting of academic drug trials

   Type of study  
  Total n (%) Exploratory n (%*) Confirmatory n (%*) P
Number of controlled trials 76 26 50 -
Design     
Parallel 38 (50 %) 11 (42 %) 27 (54 %) 0.33
Cross-over 37 (49 %) 14 (54 %) 23 (46 %) 0.52
Other 1 (1 %) 1 (4 %) 0 (0 %) 0.34**
Blinding 57 (75 %) 16 (62 %) 41 (82 %) 0.051
Randomization 69 (91 %) 20 (77 %) 49 (98 %) 0.006
  1. *Prevalence in each subgroup; for example, a parallel design was used in 27 of the confirmatory trials (54 %)