Table 2 Study centres and settings of the trial

University of Witten/Herdecke

Network of teaching and research practices of the university; list of all GP practices providing care for patients with statutory public health insurance in the region of South Eastern North-Rhine-Westfalia

Rostock University Medical Centre

List of all GP practices providing care for patients with statutory public health insurance in the region of Mecklenburg-Western Pomerania and parts of Berlin

Paracelsus Medical University

List of all GP practices of the province of Salzburg; list of all GP practices providing care for patients with statutory public health insurance in the region of South Eastern Bavaria

South Tyrolian Academy of General Practice

Research network of primary care practices of the Scuola Veneta di Medicina Generale (SVeMG)

University of Manchester

Primary Care Research Network East of England (PCRN EoE) and others