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Table 1 PICO research question of the PRIMA-eDS trial

From: Polypharmacy in chronic diseases–Reduction of Inappropriate Medication and Adverse drug events in older populations by electronic Decision Support (PRIMA-eDS): study protocol for a randomized controlled trial

PICO-Item Research question
P (patients) Patients aged ≥75 years taking ≥8 drugs in primary care
I (intervention) GPs of enrolled patients with access to the PRIMA-eDS tool
C (comparison) GPs of enrolled patients without access to the PRIMA-eDS tool (usual care)
O (outcome) Non-elective hospitalization or death within an observation time of 2 years
  1. PRIMA-eDS Polypharmacy in chronic diseases–Reduction of Inappropriate Medication and Adverse drug events in older populations by electronic Decision Support