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Table 1 PICO research question of the PRIMA-eDS trial

From: Polypharmacy in chronic diseases–Reduction of Inappropriate Medication and Adverse drug events in older populations by electronic Decision Support (PRIMA-eDS): study protocol for a randomized controlled trial

PICO-Item

Research question

P (patients)

Patients aged ≥75 years taking ≥8 drugs in primary care

I (intervention)

GPs of enrolled patients with access to the PRIMA-eDS tool

C (comparison)

GPs of enrolled patients without access to the PRIMA-eDS tool (usual care)

O (outcome)

Non-elective hospitalization or death within an observation time of 2 years

  1. PRIMA-eDS Polypharmacy in chronic diseases–Reduction of Inappropriate Medication and Adverse drug events in older populations by electronic Decision Support