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Table 3 Nutrient content of vitamins and micronutrients used in supplementation trials outlined in Fig. 2

From: Perspectives on the design and methodology of periconceptional nutrient supplementation trials

Trial country [reference]

Ca mg

Cu mg

Folic acid mg

I μg

Fe mg

Mg mg

Mn mg

Niacin mg

P mg

K mg

Se μg

Zn mg

Biotin μg

Vitamins

B1 mg

B2 mg

A μg

B12 μg

C mg

D IU

E mg

K μg

B5 mg

B6 mg

Wales [20]

-

-

4

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Gambia [27, 31]

-

2

0.4

150

30

-

-

18

-

-

65

15

-

1.4

1.4

240

2.6

70

200

1

-

-

1.9

Hungary [30]

125

1

0.8

-

60

100

1

19

125

100

-

7.5

200

1.6

1.8

1,800

4

100

500

1

-

-

2.6

Bangladesh [24]

-

-

0.4

-

60

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

India [25]

240

-

4

-

120

-

-

15

-

-

-

10

-

2.5

2.5

1,200

-

40

400

-

-

-

2

Cuba [36]

-

-

5

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Vietnam 1 [33]

-

-

3.5

-

60 a

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Netherlands [37]

-

-

0.4b

                    

China 1 [34]

-

-

0.4

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

China 2 [32, 35] c

100

2

0.4

-

10

30

3

14

77

4

30

10

100

1.4

1.4

169

3

60

200

8

-

4

-

Burkina Faso [21]

-

-

2.8

-

60

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Ireland [22]

480

-

0.36

-

50

-

-

15

-

-

-

-

-

1.5

1.5

1,200

-

40

400

-

-

-

1

Algeria [38]

-

-

-

240

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Multi-country 1 [23]

-

-

4

-

-

-

-

13

-

-

-

-

-

1.5

1.5

1,200

-

40

400

-

-

-

1

Multi-country 2 [29]d

280

4

0.4

250

20

65

2.6

36

190

200

130

15

-

2.8

2.8

800

5.2

100

1,000

20

45

7

3.8

Vietnam 2 c [26]

-

2

2.8

150

60

-

-

18

-

-

65

15

-

1.4

1.4

800

2

70

600

10

-

-

-

Nepal [28]

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

7,000

-

-

-

5

-

-

-

  1. aWeekly dose of 60 mg increased to 120 mg week when pregnant. Trial compared weekly with a daily dose of 60 mg iron and 250 μg folic acid
  2. bFolic acid 0.4 or 0.5 mg and 15 % used as part of a multivitamin supplement regimen
  3. cIn addition 100 μg molybdenum
  4. dNutrient content in lipid-based supplement containing: 118 kcal energy, 2.6 g protein, 10 g fat, 4.59 g linoleic acid, 0.59 g α-linolenic acid
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Trials

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