TY - JOUR AU - Thompson, W. R. PY - 1933 DA - 1933// TI - On the likelihood that One unknown probability exceeds another in view of the evidence of Two samples JO - Biometrika VL - 25 UR - https://doi.org/10.1093/biomet/25.3-4.285 DO - 10.1093/biomet/25.3-4.285 ID - Thompson1933 ER - TY - STD TI - Bauer P, Bretz F, Dragalin V, König F, Wassmer G. Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls. Stat Med. 2015 Mar 16. doi: 10.1002/sim.6472 ID - ref2 ER - TY - JOUR AU - Todd, S. PY - 2007 DA - 2007// TI - A 25-year review of sequential methodology in clinical studies JO - Stat Med VL - 26 UR - https://doi.org/10.1002/sim.2763 DO - 10.1002/sim.2763 ID - Todd2007 ER - TY - JOUR AU - Morgan, C. C. AU - Huyck, S. AU - Jenkins, M. AU - Chen, L. AU - Bedding, a. AU - Coffey, C. S. PY - 2014 DA - 2014// TI - Adaptive design: results of 2012 survey on perception and Use JO - Ther Innov Regul Sci VL - 48 UR - https://doi.org/10.1177/2168479014522468 DO - 10.1177/2168479014522468 ID - Morgan2014 ER - TY - JOUR AU - Elsäßer, A. AU - Regnstrom, J. AU - Vetter, T. AU - Koenig, F. AU - Hemmings, R. J. AU - Greco, M. PY - 2014 DA - 2014// TI - Adaptive clinical trial designs for European marketing authorization: a survey of scientific advice letters from the European medicines agency JO - Trials VL - 15 UR - https://doi.org/10.1186/1745-6215-15-383 DO - 10.1186/1745-6215-15-383 ID - Elsäßer2014 ER - TY - JOUR AU - Quinlan, J. AU - Gaydos, B. AU - Maca, J. AU - Krams, M. PY - 2010 DA - 2010// TI - Barriers and opportunities for implementation of adaptive designs in pharmaceutical product development JO - Clin Trials VL - 7 UR - https://doi.org/10.1177/1740774510361542 DO - 10.1177/1740774510361542 ID - Quinlan2010 ER - TY - JOUR AU - Chow, S. -. C. AU - Corey, R. PY - 2011 DA - 2011// TI - Benefits, challenges and obstacles of adaptive clinical trial designs JO - Orphanet J Rare Dis VL - 6 UR - https://doi.org/10.1186/1750-1172-6-79 DO - 10.1186/1750-1172-6-79 ID - Chow2011 ER - TY - JOUR AU - Chang, M. AU - Chow, S. -. C. AU - Pong, A. PY - 2006 DA - 2006// TI - Adaptive design in clinical research: issues, opportunities, and recommendations JO - J Biopharm Stat VL - 16 UR - https://doi.org/10.1080/10543400600609718 DO - 10.1080/10543400600609718 ID - Chang2006 ER - TY - JOUR AU - Kairalla, J. a. AU - Coffey, C. S. AU - Thomann, M. a. AU - Muller, K. E. PY - 2012 DA - 2012// TI - Adaptive trial designs: a review of barriers and opportunities JO - Trials VL - 13 UR - https://doi.org/10.1186/1745-6215-13-145 DO - 10.1186/1745-6215-13-145 ID - Kairalla2012 ER - TY - JOUR AU - Coffey, C. S. AU - Levin, B. AU - Clark, C. AU - Timmerman, C. AU - Wittes, J. AU - Gilbert, P. PY - 2012 DA - 2012// TI - Overview, hurdles, and future work in adaptive designs: perspectives from a National Institutes of Health-funded workshop JO - Clin Trials VL - 9 UR - https://doi.org/10.1177/1740774512461859 DO - 10.1177/1740774512461859 ID - Coffey2012 ER - TY - JOUR AU - Jaki, T. PY - 2013 DA - 2013// TI - Uptake of novel statistical methods for early-phase clinical studies in the UK public sector JO - Clin Trials VL - 10 UR - https://doi.org/10.1177/1740774512474375 DO - 10.1177/1740774512474375 ID - Jaki2013 ER - TY - JOUR AU - Dimairo, M. AU - Boote, J. AU - Julious, S. A. AU - Nicholl, J. P. AU - Todd, S. PY - 2015 DA - 2015// TI - Missing steps in a staircase: a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials JO - Trials VL - 16 UR - https://doi.org/10.1186/s13063-015-0958-9 DO - 10.1186/s13063-015-0958-9 ID - Dimairo2015 ER - TY - STD TI - UKCRC Registered Clinical Trials Units Network. [http://www.ukcrc-ctu.org.uk/] Date accessed 14 November 2014. UR - http://www.ukcrc-ctu.org.uk/ ID - ref13 ER - TY - STD TI - NIHR. NIHR Annual Report 2013/14. NIHR; 2015. [http://www.nihr.ac.uk/documents/about-NIHR/NIHR-Publications/NIHR-Annual-Reports/NIHR%20Annual%20Report%202013_2014.pdf]. Date accessed 1 June 2015. UR - http://www.nihr.ac.uk/documents/about-NIHR/NIHR-Publications/NIHR-Annual-Reports/NIHR%20Annual%20Report%202013_2014.pdf ID - ref14 ER - TY - STD TI - Health Technology Assessment (HTA) Programme. [http://www.nets.nihr.ac.uk/programmes/hta]. Date accessed 20 August 2014. UR - http://www.nets.nihr.ac.uk/programmes/hta ID - ref15 ER - TY - STD TI - NIHR HTA Programme: Our people. [http://www.nets.nihr.ac.uk/programmes/hta/our-people] Date accessed 20 August 2014. UR - http://www.nets.nihr.ac.uk/programmes/hta/our-people ID - ref16 ER - TY - STD TI - Vagias, WM. (2006). Likert-type scale response anchors. Clemson International Institute for Tourism & Research Development, Department of Parks, Recreation and Tourism Management. Clemson University. [https://www.clemson.edu/centers-institutes/tourism/documents/sample-scales.pdf]. Date accessed 11 November 2013. UR - https://www.clemson.edu/centers-institutes/tourism/documents/sample-scales.pdf ID - ref17 ER - TY - JOUR AU - Andrich, D. PY - 1978 DA - 1978// TI - A rating formulation for ordered response categories JO - Psychometrika VL - 43 UR - https://doi.org/10.1007/BF02293814 DO - 10.1007/BF02293814 ID - Andrich1978 ER - TY - STD TI - RUMM Laboratory Pty Ltd. RUMM2030. [http://www.rummlab.com.au/] Date accessed 20 August 2014. UR - http://www.rummlab.com.au/ ID - ref19 ER - TY - JOUR AU - Bennett, C. AU - Khangura, S. AU - Brehaut, J. C. AU - Graham, I. D. AU - Moher, D. AU - Potter, B. K. PY - 2011 DA - 2011// TI - Reporting guidelines for survey research: An analysis of published guidance and reporting practices JO - PLoS Med VL - 8 ID - Bennett2011 ER - TY - STD TI - NIHR Clinical Trials Unit (CTU) Support Funding. [http://www.nets.nihr.ac.uk/programmes/ctu] Date accessed 14 November 2014. UR - http://www.nets.nihr.ac.uk/programmes/ctu ID - ref21 ER - TY - STD TI - MRC Network of Hubs for Trials Methodology Research. [http://www.methodologyhubs.mrc.ac.uk/] Date accessed 14 November 2014. UR - http://www.methodologyhubs.mrc.ac.uk/ ID - ref22 ER - TY - JOUR AU - Montori, V. M. AU - Devereaux, P. J. AU - Adhikari, N. K. J. AU - Burns, K. E. A. AU - Eggert, C. H. AU - Briel, M. PY - 2005 DA - 2005// TI - Randomized trials stopped early for benefit: a systematic review JO - JAMA VL - 294 UR - https://doi.org/10.1001/jama.294.17.2203 DO - 10.1001/jama.294.17.2203 ID - Montori2005 ER - TY - JOUR AU - Wilcox, R. A. AU - Djulbegovic, B. AU - Moffitt, H. L. AU - Guyatt, G. H. AU - Montori, V. M. PY - 2008 DA - 2008// TI - Randomized trials in oncology stopped early for benefit JO - J Clin Oncol VL - 26 UR - https://doi.org/10.1200/JCO.2007.13.6259 DO - 10.1200/JCO.2007.13.6259 ID - Wilcox2008 ER - TY - JOUR AU - Bassler, D. AU - Montori, V. M. AU - Briel, M. AU - Glasziou, P. AU - Guyatt, G. PY - 2008 DA - 2008// TI - Early stopping of randomized clinical trials for overt efficacy is problematic JO - J Clin Epidemiol VL - 61 UR - https://doi.org/10.1016/j.jclinepi.2007.07.016 DO - 10.1016/j.jclinepi.2007.07.016 ID - Bassler2008 ER - TY - STD TI - Detry M, Lewis R, Broglio K, Connor J. Standards for the design, conduct, and evaluation of adaptive randomized clinical trials. 2012.[http://www.pcori.org/assets/Standards-for-the-Design-Conduct-and-Evaluation-of-Adaptive-Randomized-Clinical-Trials.pdf]. Date accessed 12 July 2014 UR - http://www.pcori.org/assets/Standards-for-the-Design-Conduct-and-Evaluation-of-Adaptive-Randomized-Clinical-Trials.pdf ID - ref26 ER - TY - JOUR AU - Craig, P. AU - Dieppe, P. AU - Macintyre, S. AU - Michie, S. AU - Nazareth, I. AU - Petticrew, M. PY - 2008 DA - 2008// TI - Developing and evaluating complex interventions: the new Medical Research Council guidance JO - BMJ VL - 337 UR - https://doi.org/10.1136/bmj.a1655 DO - 10.1136/bmj.a1655 ID - Craig2008 ER - TY - STD TI - FDA. Adaptive designs for medical device clinical studies: draft guidance for industry and Food and Drug Administration staff. 2015.[http://www.fda.gov/ucm/groups/fdagov-public/@fdagov-meddev-gen/documents/document/ucm446729.pdf]. Date accessed 20 May 2015. UR - http://www.fda.gov/ucm/groups/fdagov-public/@fdagov-meddev-gen/documents/document/ucm446729.pdf ID - ref28 ER - TY - STD TI - Lin M, Lee S, Zhen B, Scott J, Horne A, Solomon G, Russek-Cohen E. CBER’s experience with adaptive design clinical trials. Ther Innov Regul Sci. 2015:2168479015604181. [http://dij.sagepub.com/content/early/2015/09/15/2168479015604181.abstract]. UR - http://dij.sagepub.com/content/early/2015/09/15/2168479015604181.abstract ID - ref29 ER - TY - JOUR AU - Bower, P. AU - Brueton, V. AU - Gamble, C. AU - Treweek, S. AU - Smith, C. T. AU - Young, B. PY - 2014 DA - 2014// TI - Interventions to improve recruitment and retention in clinical trials: a survey and workshop to assess current practice and future priorities JO - Trials VL - 15 UR - https://doi.org/10.1186/1745-6215-15-399 DO - 10.1186/1745-6215-15-399 ID - Bower2014 ER - TY - JOUR AU - Tudur Smith, C. AU - Hickey, H. AU - Clarke, M. AU - Blazeby, J. AU - Williamson, P. PY - 2014 DA - 2014// TI - The trials methodological research agenda: results from a priority setting exercise JO - Trials VL - 15 UR - https://doi.org/10.1186/1745-6215-15-32 DO - 10.1186/1745-6215-15-32 ID - Tudur Smith2014 ER -