Inclusion criteria | Exclusion criteria |
---|---|
Have severe limb ischaemia due to infra-popliteal, +/− femoropopliteal disease | Have an anticipated life expectancy of < 6 months |
Be judged by responsible clinicians (consultant vascular surgeon, interventional radiologist, and diabetologists) working as part of a multi-disciplinary team to require early revascularisation in addition to best medical therapy, foot and wound care. | Are unable to provide consent due to incapacity |
Have adequate inflow to support the randomised infra-popliteal intervention (if not, patients can be randomised to have their allocated infra-popliteal intervention at the same time or after the inflow procedure). | Are a non-English speaker where translation services are inadequate to provide informed consent |
Be judged suitable for both vein bypass and best endovascular treatment following diagnostic imaging and a formal documented multi-disciplinary team meeting. | Are judged unsuitable for either revascularisation strategy by the responsible clinician |
Tissue loss considered to be primarily of venous aetiology |