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Table 4 Characteristics of included studies – deferred consent

From: Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness

Reference Country Clinical context Study design Study aim Scenario: real or hypothetical Study sample
Respondents Direct experience of clinical context or condition Direct experience of consent model
Potential research participants
Qualitative or mixed methods studies
30. Woolfall 2014b UK Paediatric – status epilepticus Qualitative (focus groups, interviews) Inform study design Proposed trial evaluating new treatment for status epilepticus 17 parents Mixed No
Survey studies
31. Chenaud 2009a Switzerland ICU Survey (Self-administered) Evaluate preferences Hypothetical scenarios of ICU research 67 patients; 52 relatives from recent ICU admission Yes No
32. Gamble 2012b UK Meningitis Survey (self-administered) Investigate views Proposed trial evaluating two currently used treatments for emergency resuscitation and treatment 68 families Yes No
33. Gigon 2013a Switzerland ICU Survey (self-administered) Evaluate choice Hypothetical scenarios of ICU research 185 patients, 125 relatives following ICU discharge Yes No
34. Potter 2013 Australia ICU Survey (self-administered) Post-trial evaluation Clinical trial evaluating two strategies for maintaining blood sugar in ICU 210 trial participants Yes Yes
35. Scales 2009a Canada Critical illness Survey (interview) Survey preferences Hypothetical study scenarios of research during critical illness 240 survivors of critical illness Yes No
Clinical, research staff or regulators
Survey studies
36. Cook 2008b Canada, Australia, New Zealand Critical illness Survey (self-administered) Evaluate experience, beliefs, and practices Hypothetical – enrolment of critically ill children and adults 284 clinicians caring for critically ill patients Yes Yes
37. Duffett 2011a Canada Critical care research Survey (self-administered) Evaluate attitudes and beliefs Hypothetical scenario of double-blind, placebo-controlled, RCT evaluating single dose of medication perceived by REB as minimal risk 98 ICU researchers; 52 members of hospital research ethics boards. Yes Possible
38. Woolfall 2013b UK Paediatric – status epilepticus Survey (self-administered) Evaluate views and experiences Hypothetical 45 clinical staff Yes Mixed
  1. acompares different consent models
  2. bpaediatrics