Table 4 Univariate analysis of factors influencing patients’ views on whether they would participate in a trial involving a research biopsy
Patient characteristic | Yes | Odds ratio (95 % CI) | p valuea |
|---|---|---|---|
N (%) | |||
(n = 78) | |||
Age | |||
< 65 years | 37 (57 %) | 1.0 | |
≥ 65 years | 41 (67 %) | 1.55 (0.75–3.21) | 0.236 |
Gender | |||
Male | 59 (64 %) | 1.0 | |
Female | 19 (56 %) | 0.71 (0.32–1.58) | 0.398 |
Tumour type | |||
Colorectal | 30 (60 %) | 1.0 | |
Oesophagogastric | 37 (73 %) | 1.76 (0.76–4.06) | 0.184 |
Performance status (PS) | |||
0 | 30 (67 %) | 1.0 | |
1 | 36 (59 %) | 0.72 (0.32–1.61) | 0.423 |
2 | 7 (70 %) | 1.17 (0.26-5.16) | 0.839 |
Previously participated in a clinical trial | |||
Yes | 13 (65 %) | 1.0 | |
No | 64 (61 %) | 1.19 (0.44–3.23) | 0.733 |
Number of previous lines of treatment | |||
0 | 24 (47 %) | 1.0 | |
1 | 31 (67 %) | 2.33 (1.02–5.31) | 0.045 |
2+ | 22 (79 %) | 4.13 (1.43–11.9) | 0.009 |
Type of treatment | |||
Palliative | 60 (69 %) | 1.0 | |
Curative | 18 (46 %) | 0.39 (0.18–0.84) | 0.015 |
CTIMP | |||
No | 44 (60 %) | 1.0 | |
Yes | 19 (53 %) | 0.74 (0.33–1.65) | 0.457 |