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Table 3 Factors which influenced patients’ decision to participate in a clinical trial

From: Patients’ willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey

Reason CTIMP Pre-screening Non-CTIMP All
N (%) N (%) N (%) (n = 241)
(n = 63) (n = 28) (n = 150)
Patient felt the trial offered the best available treatment 49 (78 %) 16 (57 %) 57 (39 %) 122 (51 %)
Patient felt the trial result could benefit others 53 (84 %) 24 (86 %) 143 (96 %) 220 (92 %)
Patient wanted to contribute to scientific research 37 (59 %) 16 (57 %) 111 (74 %) 164 (68 %)
Patient felt they would be monitored more closely 28 (44 %) 9 (32 %) 42 (28 %) 79 (33 %)
Patient felt they would have better quality care 20 (32 %) 5 (18 %) 24 (16 %) 49 (20 %)
Patient’s family were keen for patient to participate 24 (38 %) 8 (29 %) 20 (13 %) 52 (22 %)
Patient trusted the doctor treating them 38 (60 %) 10 (36 %) 73 (49 %) 121 (50 %)
Patient felt that otherwise their cancer will get worse 17 (27 %) 3 (11 %) 13 (9 %) 33 (14 %)
Other reason 4 (6 %) 0 (0 %) 8 (5 %) 12 (5 %)
  1. Key: CTIMP = Clinical Trial of an Investigational Medicinal Product, pre-screening = molecular pre-screening to determine potential eligibility for a specific CTIMP study