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Overall peak external frontal knee moment and impulse
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3D gait analysis during walking
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Secondary outcome parameters
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Frontal and sagittal kinematics and kinetics for hip, knee and ankle joints
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3D gait analysis during walking and stair climbing
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KOOS subscales (Austrian-German version)
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Knee function in daily living (ADL)
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Knee function in sport and recreation (Sport/Rec)
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Knee-related quality of life (QOL)
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Knee pain and other symptoms
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Changes of function and strength of the targeted muscle groups
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Physical examination/orthopaedic status
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Adherence to training programme
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Percentage of completed sessions among the number of intended exercise sessions
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Ratings of knee-related pain
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7-point ordinal scale (followed for the duration of the intervention)
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Other outcome parameters
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Cardiopulmonary testing
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Symptom-limited cardiopulmonary exercise testing on a cycle ergometer
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Anthropometry
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Anthropometric measurements
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Body composition
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Bioimpedance analysis
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Nutritional status
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24-hour recall method (daily, self-reported consumption of food-intake)
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Psychological status
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AD-EVA test inventory, Child Behaviour Checklist (CBCL/4-18 )
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Blood samples
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Growth hormones (GH, IGFBP3, AP) and inflammation (procalcin, TGF-α, IL-8) from venous blood samples
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All measures will be recorded at baseline and follow-up unless stated otherwise
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