Table 2 Study schedule

Visit

R1

R2

R3

R4

yr 1

F1

F2

F3

yr 2

F4

F5

F6

yr 3

F7

F8

F9

Time

−4 wks

−3 wks

−2 wks

−1 wk

mo 1

mo 4

mo 8

mo 12

mo 13

mo 16

mo 20

mo 24

mo 25

mo 28

mo 32

mo 36

Enrollment

 Eligibility screen

 Medical history

X

 Clinical examination

X

 LTPA questionnaire

X

 Confirmation of sedentary habits/ physical inactivity

X

 informed consent

X

 Demographics

X

 Cardiologic evaluation

X

 Allocation

X

Interventions

 CON group

 Physician recommends increasing daily PA

X

X

X

 INT group

 Theoretical session

X

X

X

 Theoretical and practical sessions

X

X

X

 Both: Standard care

Prescription

X

 Adjustment

X^a

X^a

X^a

X^a

X^a

X^a

X^a

X^a

X^a

Assessments

 Physical fitness

 Run-in familiarization session

X

X

 Assessment

X

X

X

X

 Accelerometer (key)

 Delivery of the key (and daily diary)

X

X

X

X

X

X

X

X

X

X

 Return of the key (and daily diary)

X

X

X^a

X^a

X^a

X^a

X^a

X^a

X^a

X^a

 CV risk factors

 Anthropometric data

X

X

X

X

X

X

X

X

X

X

 Bioimpedence

X

X

X

X

X

X

X

X

X

X

 Blood pressure

X

X

X

X

X

X

X

X

X

X

 Blood and urine testing

X

X

X

X

X

X

X

X

X

X

 Questionnaires

 MS

X

X

X

X

X

X

X

 WHO-5

X

X

X

X

X

X

X

 SF-36

X

X

X

X

X

X

X