Placebo (n = 24) | Test (n = 25) | |
---|---|---|
Hemoglobin A1c (%)a | ||
0 week | 6.4 ± 0.16 | 6.4 ± 0.14 |
6 week | 6.2 ± 0.14*** | 6.1 ± 0.13** |
Insulin (uU/mL)a | ||
0 minutes | ||
0 week | 9.5 ± 0.77 | 11.1 ± 1.03 |
6 week | 9.2 ± 0.68 | 12.4 ± 2.49 |
30 minutes | ||
0 week | 30.5 ± 3.93 | 43.7 ± 8.26 |
6 week | 21.3 ± 3.03* | 41.3 ± 8.60 |
60 minutes | ||
0 week | 44.5 ± 6.35 | 58.5 ± 9.34 |
6 week | 34.9 ± 5.06* | 46.3 ± 8.21* |
120 minutes | ||
0 week | 46.7 ± 7.65 | 56.1 ± 10.58 |
6 week | 36.3 ± 6.49† | 42.1 ± 7.46† |
Insulin AUC (uU/mL per hour)a | ||
0 week | 74.3 ± 8.66 | 96.6 ± 13.98 |
6 week | 57.3 ± 7.72** | 79.5 ± 11.74* |
C-peptide (ng/mL)a | ||
0 minutes | ||
0 week | 2.1 ± 0.16 | 2.5 ± 0.18 |
6 week | 2.1 ± 0.15 | 2.7 ± 0.33 |
30 minutes | ||
0 week | 5.1 ± 0.38 | 6.0 ± 0.60 |
6 week | 4.4 ± 0.39* | 5.9 ± 0.71 |
60 minutes | ||
0 week | 7.5 ± 0.49 | 8.6 ± 0.75 |
6 week | 6.8 ± 0.47* | 8.0 ± 0.68 |
120 minutes | ||
0 week | 9.4 ± 0.67 | 9.1 ± 0.69 |
6 week | 9.2 ± 0.65 | 8.4 ± 0.64 |
C-peptide AUC (ng/mL)a | ||
0 week | 13.4 ± 0.79 | 14.6 ± 1.10 |
6 week | 12.4 ± 0.83* | 13.8 ± 1.01 |