Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Fig. 2 | Trials

Fig. 2

From: A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results

Fig. 2

Proportion of real-world patients ineligible in randomized controlled trials (RCTs) after application of inclusion/exclusion criteria. Method B studies. Some individual studies reported multiple ineligibility rates derived from the application of selection criteria from a number of different RCTs to a single real-world population. Hence, in the 34 studies that employed Method B, 54 different ineligibility rates were calculated

Back to article page