Table 2 Parameter estimates for the three potential designs for the motivating example under the maximum sample size required to satisfy power. A simulation was performed to calculate expected sample size, Type I error and power
From: Generalizing boundaries for triangular designs, and efficacy estimation at extended follow-ups
Estimate | Design 1 | Design 2 | Design 3 |
|---|---|---|---|
| Â | (3 analyses) | (4 analyses) | (7 analyses) |
Maximum sample size | 86 | 86 | 102 |
Expected sample size under H0 | 46 | 44 | 43 |
Expected sample size under H1 | 49 | 49 | 48 |
Type I error | 0.0471 | 0.0453 | 0.044 |
Power | 0.962 | 0.964 | 0.976 |