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Table 3 Angiographic characteristics and procedural complications, expressed as percentages or as median and interquartile ranges

From: Who is eligible for randomized trials? A comparison between the exclusion criteria defined by the ISCHEMIA trial and 3102 real-world patients with stable coronary artery disease undergoing stent implantation in a single cardiology center

Variable

All patients

Group A

Group B

P

(Patients who met ISCHEMIA exclusion criteria)

(Patients who did not meet ISCHEMIA exclusion criteria)

(A vs. B)

n = 3102

n = 1900

n = 1202

Angiographic characteristics

Multivessel disease

636 (20.5)

419 (22.1)

217 (18.1)

0.01

Significant stenosis; left main coronary artery

157 (5.1)

129 (6.8)

28 (2.3)

<0.001

Significant stenosis – left anterior descending or diagonal

1781 (57.4)

1092 (57.5)

689 (57.3)

0.94

Significant stenosis – circumflex or obtuse marginal

1620 (52.2)

579 (48.2)

1041 (54.8)

<0.001

Significant stenosis – right coronary artery

1746 (56.3)

1045 (55)

701 (58.3)

0.07

Number of vessels, percutaneous coronary intervention

1 (1–1)

1 (1–1)

1 (1–1)

0.005

Number of stents

1 (1–2)

1 (1–2)

1 (1–2)

0.005

Implanted stent

bare metal stent

1785 (57.5)

1087 (57.2)

698 (58.1)

 

drug-eluting stent

1211 (39)

743 (39.1)

468 (38.9)

0.57

bare metal stent and drug-eluting stent

106 (3.5)

70 (3.7)

36 (3)

 

Complications

Myocardial infarction

40 (1.3)

27 (1.4)

13 (1.1)

0.51

Stroke or transient ischemia attack

10 (0.3)

9 (0.5)

1 (0.1)

0.1

Bleeding

52 (1.7)

29 (1.5)

23 (1.9)

0.47

Blood transfusion

30 (1.0)

22 (1.2)

8 (0.7)

0.19

Dissection

159 (5.1)

108 (5.7)

51 (4.2)

0.08

Repeat of percutaneous transluminal coronary angioplasty

9 (0.3)

5 (0.3)

4 (0.3)

0.74

Urgent coronary artery bypass graft

2 (0.1)

1 (0.1)

1 (0.1)

1.0

Sudden cardiac arrest

30 (1)

16 (0.8)

14 (1.2)

0.45

Mortality

366 (11.9)

287 (15.1)

79 (6.6)

<0.001