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Table 4 RIFLE criteria as defined by Bellomo et al. [25]

From: Comparison of 6 % hydroxyethyl starch and 5 % albumin for volume replacement therapy in patients undergoing cystectomy (CHART): study protocol for a randomized controlled trial

Category GFR criteria Urine Output (UO) criteria
Risk Increased creatinine × 1.5 or GFR decrease > 25 % UO <0.5 ml/kg/h for 6 h
Injury Increased creatinine × 2 or GFR decrease > 50 % UO <0.5 ml/kg/h for 12 h
Failure Increase creatinine × 3 or GFR decrease > 75 % UO <0.3 ml/kg/h for 24 h or anuria for 12 h
Loss Persistent ARF = complete loss of kidney function >4 wk
ESKD End-stage kidney disease (>3 mo)
  1. ARF acute renal failure, ESKD end-stage kidney disease, GFR glomerular filtration rate, RIFLE risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function, and end-stage kidney disease, UO urine output