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Table 2 Algorithm of infusions and transfusion in the operating room and intensive care unit

From: Comparison of 6 % hydroxyethyl starch and 5 % albumin for volume replacement therapy in patients undergoing cystectomy (CHART): study protocol for a randomized controlled trial

Hemodynamics  
ASA I and II patients without cardiac diseases or cerebral insufficiency:  
  Stroke volume variation (SVV) <12 %  
  Cardiac index (CI) > 2.5 L/min/m2  
  MAD >60 mmHg  
ASA III and IV patients or patients with cardiac diseases or cerebral insufficiency:  
  SVV <12 %  
  CI >2.5 L/min/m2  
  MAD >70 mmHg  
  Central venous oxygen saturation >70 % or mixed venous oxygen saturation >65 %  
To reach the desired parameter:  
  Start with infusion protocol (see below)  
  If not successful within 15 minutes:  
  Start with norepinephrine as first-choice vasopressor  
Infusion protocol  
  Replacement of urine output with Ringer’s acetate solution in a 1:1 ratio  
  Additionally, 500 ml of crystalloids for insensible sweating  
  Replacement of blood and protein losses dependent on treatment assignment, with either HA 5 % or HES 6 % in a 1:1 ratio up to a transfusion trigger point or a maximum of 50 ml/kg/day  
  Additionally up to 1500 ml of colloids for the protein loss into the third compartment