Table 3 Results of analysis of covariance (ANCOVA) of full analysis set (FAS)

FSS

A

4.67 (1.27)

3.39 (1.12)

<0.001

−1.14 (−1.57, −0.71)

3.32 (1.17)

<0.001

−1.01 (−1.48, −0.55)

B

4.75 (1.07)

3.62 (1.13)

<0.001

−0.95 (−1.38, −0.52)

3.58 (1.20)

<0.001

−0.80 (−1.26, −0.34)

C

4.48 (1.27)

4.43 (1.19)

-

-

4.24 (1.25)

-

-

SRI-short form

A

62.56 (17.95)

43.07 (15.49)

<0.001

−15.24 (−21.32, −9.16)

43.61 (15.31)

<0.001

−15.01 (−21.96, −8.06)

B

55.67 (14.40)

42.65 (14.24)

<0.001

−11.58 (−17.45, −5.72)

40.19 (13.57)

<0.001

−14.97 (−21.67, −8.26)

C

60.04 (18.16)

56.82 (18.10)

-

-

57.36 (20.30)

-

-

BDI

A

16.41 (8.36)

9.43 (6.98)

<0.001

−5.03 (−7.60, −2.47)

10.02 (6.40)

<0.001

−4.74 (−7.56, −1.91)

B

15.00 (7.67)

9.04 (7.61)

<0.001

−4.63 (−7.17, −2.10)

8.20 (7.01)

<0.001

−5.88 (−8.67, −3.09)

C

15.30 (7.05)

13.84 (6.80)

-

-

14.22 (8.32)

-

-

NRS

A

6.59 (1.44)

4.56 (2.09)

<0.001

−1.96 (−2.72, −1.20)

4.78 (2.32)

<0.001

−1.64 (−2.51, −0.78)

B

6.55 (1.27)

4.58 (1.70)

<0.001

−1.93 (−2.68, −1.18)

4.59 (1.92)

<0.001

−1.81 (−2.67, −0.96)

C

6.40 (1.40)

6.46 (1.39)

-

-

6.34 (1.70)

-

-

EQ-5D

A

0.84 (0.10)

0.96 (0.11)

0.025

0.04 (0.00, 0.08)

0.91 (0.11)

0.008

0.06 (0.01, 0.11)

B

0.87 (0.09)

0.91 (0.09)

0.107

0.03 (−0.01, 0.07)

0.93 (0.09)

0.005

0.06 (0.02, 0.11)

C

0.88 (0.11)

0.88 (0.09)

-

-

0.87 (0.15)

-

-