Bacchieri, 2010 [29]
|
Poisson regression
|
Rate ratio
|
Both
|
Robust standard errors
|
Time-to-event
|
No
|
Fixed effect (no interaction)
|
None
|
None
|
Minor
|
Bashour, 2013 [22]
|
Linear regression
|
Mean difference
|
Both
|
Random effects
|
No
|
Yes
|
Fixed effect
|
None
|
None
|
Major
|
(no interaction)
|
Durovni, 2013 [12]
|
Cox regression
|
Rate ratio
|
Within-step only, plus frailty
|
Random effects
|
Time-to-event
|
Yes
|
Conditional
|
Major
|
None
|
Minor
|
Fuller, 2012 [23]
|
Logistic regression
|
Odds ratio
|
Both
|
Random effects
|
Yes, not explicitly accounted for
|
Yes
|
Fixed effects
|
Major
|
None (per-protocol analysis using observed lags)
|
Major
|
(no interaction)
|
Gruber 2013 [21]
|
Linear regression, Log-Poisson regression
|
Risk difference, risk ratio
|
Both
|
Robust standard errors, GEE
|
Yes, not explicitly accounted for
|
Yes, in secondary analyses
|
Fixed effect
|
Major
|
None
|
Low
|
(no interaction)
|
Horner, 2012 [27]
|
Logistic regression
|
Odds ratio
|
Both
|
Random effects
|
Yes, not explicitly accounted for
|
Yes
|
Fixed effect
|
Minor
|
None
|
Minor
|
(no interaction)
|
Mhurchu, 2013 [24]
|
Logistic regression
|
Odds ratio
|
Both
|
Random effects
|
Yes, pupil-level summaries and random effect
|
Yes
|
Fixed effect
|
None
|
None
|
Minor
|
(no interaction)
|
Roy, 2013 [25]
|
Logistic regression
|
Odds ratio
|
Both
|
Random effects
|
No
|
Yes
|
None
|
None
|
None
|
Minor
|
Schultz, 2014 [28]
|
Logistic regression
|
Odds ratio
|
Both
|
None: GEE not possible, and RE did not converge
|
No
|
No
|
Fixed effect
|
Minor
|
None
|
None
|
(no interaction)
|
Stern, 2014 [26]
|
Linear regression
|
Mean difference
|
Both
|
Random effects
|
Yes, multiple level random effects
|
Yes
|
Fixed effect with interaction
|
Major
|
None
|
Minor
|