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Table 4 One-year changes in psychological and metabolic outcomes in the subgroups of patients with low versus high baseline values

From: Does treatment of subsyndromal depression improve depression-related and diabetes-related outcomes? A randomised controlled comparison of psychoeducation, physical exercise and enhanced treatment as usual

 

Baseline values

Number

M (SD) Baseline to 12 months

Mean differences (95 % CI) Baseline to 12 months

Effects

F

p a

p baseline to 12 monthsb

η2

Depressive symptoms

          

(CES-D)

<16

62

10.8 (3.4)

12.0 (6.8)

1.22 (−0.82, 3.25)

Time

1.24

0.293

0.435

0.02

     

Time x group

0.99

0.412

  

≥16

117

24.1 (6.8)

20.2 (8.8)

−3.91 (−5.89, −1.93)

Time

21.27

<0.001

<0.001

0.16

     

Time x group

1.58

0.179

  

Diabetes distress (PAID)

          
 

<40

94

23.6 (10.2)

24.0 (17.2)

0.47 (−3.28, 4.22)

Time

0.98

0.371

1.00

0.01

     

Time x group

0.62

0.637

  

≥40

84

56.4 (12.3)

45.1 (20.3)

−11.51 (−16.05, −6.97)

Time

29.57

<0.001

<0.001

0.27

     

Time x group

1.10

0.356

  

HbA1c, (mmol/mol)

<53

79

46 (5)

50 (9)

3.95 (1.72, 6.19)

Time

15.05

<0.001

<0.001

0.16

      

Time x group

0.58

0.610

  
 

≥53

100

64 (10)

60 (10)

−4.27 (−7.10, −1.46)

Time

13.38

<0.0001

<0.001

0.12

      

Time x group

1.25

0.295

  

HbA1c (%)

<7.0

80

6.3 (0.5)

6.6 (0.8)

0.34 (0.14, 0.54)

Time

13.89

<0.001

<0.001

0.15

      

Time x group

0.52

0.662

  
 

≥7.0

99

8.0 (0.9)

7.6 (0.9)

−0.44 (−0.70, −0.18)

Time

14.51

<.001

<.001

0.13

      

Time x group

1.59

0.189

  

LDL-cholesterol (mmol/l)

          

<2.3

44

1.8 (0.4)

2.1 (0.7)

0.25 (0.001, 0.50)

Time

5.52

0.009

0.05

0.12

     

Time x group

1.31

0.279

  

≥2.3

135

3.4 (0.9)

3.0 (0.9)

−0.38 (−0.56, −0.19)

Time

12.22

<0.001

<0.001

0.09

    

Time x group

1.24

0.295

  
  1. atwo-sided significance of differences across time and between the groups (repeated measures ANOVA)
  2. btwo-sided significance of differences between baseline- and 12-month assessments
  3. CES-D Centre for Epidemiological Studies-Depression scale, HbA 1c glycosylated haemoglobin, LDL low-density lipoprotein, PAID Problem Areas in Diabetes scale