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Table 1 Endpoints

From: Podoconiosis treatment in northern Ethiopia (GoLBet): study protocol for a randomised controlled trial

  Endpoint details
Primary endpoint Cumulative incidence of ADLA (total number of incident episodes over the 12-month follow-up period).
Secondary endpoints Adherence to treatment
  Foot washing, use of ointment, use of bandages, elevation, exercises, use of socks and shoes.
  Clinical outcomes:
  Clinical stage of diseasea
  Lower leg and foot circumferencesb
  Presence of mossy changes
Wounds and inter-digital lesions;
Duration of ADLA days
Social outcomes:
Quality of lifec
Perceived stigmad
Economic outcomes:
Economic productivitye
  1. ADLA, acute dermatolymphangioadenitis
  2. aUsing a scale specifically developed for use in podoconiosis patients [22]
  3. bMeasured in centimetres at mid-calf and mid-foot
  4. cUsing validated Amharic translation of Dermatology Life Quality Index [23] and WHO Disability Assessment Schedule-II (WHODAS-II)
  5. dUsing scale developed to measure stigma among podoconiosis patients (24)
  6. eOther measures of economic vulnerability found to be related to podoconiosis in economic context survey