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Table 1 Comparison of included and excluded participants

From: Similarities and differences between patients included and excluded from a randomized clinical trial of vitamin d supplementation for improving glucose tolerance in prediabetes: interpreting broader applicability

Characteristics

Included

Excluded

P value

Excluded A1c 5.7-6.9 %

P value

Number of Participants

178

178

 

105

 

Continuous, Mean (SD)

Age, yrs

59.1 (6.1)

60.1 (7.7)

 

62.1 (7.5)

 

BMI, kg/m2

32.0 (2.7)

31.1 (3.5)

 

30.7 (3.4)

0.002

A1c, %

6.1 (0.2)

5.8 (0.5)

 

6.2 (0.3)

 

25(OH)D, ng/ml

14.3 (5.1)

15.2 (5.5)

 

16.1 (5.7)

 

eGFR, mL/min

85.7 (16.1)

87.1 (15.7)

 

83.4 (14.1)

 

Cholesterol, mg/dl

182.2 (32.1)

173.3 (32.9)

 

175.8 (35.4)

 

LDL, mg/dl

111.9 (27.0)

97.3 (31.2)

 

101.6 (34.0)

 

HDL, mg/dl

44.6 (10.1)

51.3 (13.9)

0.001

49.7 (11.8)

0.001

TG, mg/dl

132.8 (59.4)

124.8 (58.7)

 

122.1 (58.4)

 

AST, U/L

27.0 (10.3)

31.4 (15.6)

 

27.0 (11.1)

 

ALT, U/L

45.8 (14.1)

50.8 (20.7)

 

47.5 (17.6)

 

Charlson Index

2.20 (1.17)

2.85 (1.60)

0.001

3.11 (1.66)

0.001

Categorical, N (%)

HTN

121 (68.0)

117 (65.7)

 

68 (64.8)

 

Hyperlipidemia

97 (54.5)

84 (47.2)

 

55 (52.4)

 

DJD

58 (32.6)

68 (38.2)

 

45 (42.9)

 

CVD

29 (16.3)

31 (17.4)

 

23 (21.9)

 

Cancer

23 (12.9)

34 (19.1)

 

24 (22.9)

 

Psychiatric disorders

129 (72.5)

118 (66.3)

 

59 (56.2)

 

Anti-HTN medications

108 (60.1)

103 (57.9)

 

61 (58.1)

 

Thiazide diuretic use

53 (29.8)

37 (20.8)

 

19 (18.1)

 

Statins

69 (38.8)

61 (34.3)

 

42 (40.0)

 

Vit D supplements

30 (17.4)

48 (27.0)

 

25 (23.8)

 
  1. P values listed for significant findings compared to included group. Each excluded group was compared to included participants. P value deemed significant at P < 0.0023 after Bonferonni correction. BMI, body mass index; TG, triglycerides; HTN, hypertension; DJD, degenerative joint disease; CVD, cardiovascular disease