Table 3 Study methodology and conduct (n = 43 unless otherwise stated)
From: A systematic review of the use of an expertise-based randomised controlled trial design
Number | Percentage | |
|---|---|---|
Intervention deliverers–randomisation sequence generation | ||
Adequate | 1 | 10 |
Inadequate | 0 | 0 |
Unclear | 9 | 90 |
Intervention deliverers–randomisation allocation concealment | ||
Adequate | 1 | 10 |
Inadequate | 0 | 0 |
Unclear | 9 | 90 |
Participants–randomisation sequence generation | ||
Adequate | 25 | 58 |
Inadequate | 0 | 0 |
Unclear | 18 | 42 |
Participants–randomisation allocation concealment | ||
Adequate | 26 | 60 |
Inadequate | 2 | 5 |
Unclear | 15 | 35 |
Blinding–primary outcome assessment | ||
Yes | 12 | 28 |
No | 27 | 63 |
Unclear | 4 | 9 |
Blinding–participants | ||
Yes | 1 | 2 |
No | 34 | 79 |
Unclear | 8 | 19 |
Number of centres | ||
Reported | 42 | 98 |
Median (IQR) | 1 | (1–5) |
Study size | ||
Reported | 42 | 98 |
Median (IQR) | 111 | (62–226) |
Percentage of target size recruited | ||
Reported target size | 17 | 40 |
Median (IQR) | 101 | (94–118) |
Percentage received full intervention | ||
Reported | 31 | 74 |
Median (IQR) | 92 | (82–99) |
Cross-over to other study intervention | ||
Reported | 18 | 42 |
Median (IQR) | 0 | (0–2) |
“Third” intervention | ||
Reported | 15 | 35 |
Median (IQR) | 0 | (0–0) |