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Table 3 Study methodology and conduct (n = 43 unless otherwise stated)

From: A systematic review of the use of an expertise-based randomised controlled trial design

  Number Percentage
Intervention deliverers–randomisation sequence generation
 Adequate 1 10
 Inadequate 0 0
 Unclear 9 90
Intervention deliverers–randomisation allocation concealment
 Adequate 1 10
 Inadequate 0 0
 Unclear 9 90
Participants–randomisation sequence generation   
 Adequate 25 58
 Inadequate 0 0
 Unclear 18 42
Participants–randomisation allocation concealment
 Adequate 26 60
 Inadequate 2 5
 Unclear 15 35
Blinding–primary outcome assessment   
 Yes 12 28
 No 27 63
 Unclear 4 9
Blinding–participants   
 Yes 1 2
 No 34 79
 Unclear 8 19
Number of centres   
 Reported 42 98
 Median (IQR) 1 (1–5)
Study size   
 Reported 42 98
 Median (IQR) 111 (62–226)
Percentage of target size recruited   
 Reported target size 17 40
 Median (IQR) 101 (94–118)
Percentage received full intervention   
 Reported 31 74
 Median (IQR) 92 (82–99)
Cross-over to other study intervention   
 Reported 18 42
 Median (IQR) 0 (0–2)
“Third” intervention   
 Reported 15 35
 Median (IQR) 0 (0–0)
  1. IQR interquartile range