From: Quality of randomized controlled trials reporting in the treatment of melasma conducted in China
Item | Criteria | Description | Number of positive trials | % | Cohen’sкcoefficient | 95% CI |
---|---|---|---|---|---|---|
8 | Randomization | Description of the method used to generate the random sequence | 41 | 17 | 0.85 | 0.76 to 0.95 |
9 and 10 | Allocation concealment and implementation | Description of the method used to implement the random allocation sequence assuring the concealment until interventions are assigned | 1 | 0 | 0.75 | 0.65 to 0.88 |
11 | Blinding | Whether or not participants, those administering the interventions, or those assessing the outcomes were blinded to group assignment | 6 | 2 | 0.78 | 0.72 to 0.87 |
15 | Baseline data | An outline of baseline demographic and clinical characteristics of each group | 147 | 60 | 0.82 | 0.78 to 0.90 |
16 | Intent-to-treat analysis | Number of participants in each group included in each analysis and whether it was done by ‘intention-to-treat’ | 5 | 2 | 0.86 | 0.78 to 0.98 |