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Table 1 The characteristics of the patients and depression score and its changes in the groups

From: Vitamin C as an adjuvant for treating major depressive disorder and suicidal behavior, a randomized placebo-controlled clinical trial

Ā 

Vitamin C group (nā€‰=ā€‰21)

Placebo group (nā€‰=ā€‰22)

Ā 

Mean (SD) years of age

32.7 (8.4)

34.2 (10.3)

tā€‰=ā€‰1.5, dfā€‰=ā€‰41, Pā€‰=ā€‰.5

Number (%) of females

15 (71.4)

17 (77.2%)

X2ā€‰=ā€‰.19, dfā€‰=ā€‰1, Pā€‰=ā€‰.6

Marital status n (%)

Single

7 (31.9%)

7 (31.8%)

X2ā€‰=ā€‰.1, dfā€‰=ā€‰2, Pā€‰=ā€‰.9

Married

13 (59.1%)

14 (63.6%)

Divorced

1 (4.5%)

1 (4.5%)

Psychotic features

0

0

-

Number (%) of smokers

2 (9.1%)

2 (9.1%)

-

Positive history of being administered ECT

0

0

-

Mean (SD) of Body Mass Index

25.1 (3.4)

26.3 (6.5)

tā€‰=ā€‰.7, dfā€‰=ā€‰42, Pā€‰=ā€‰.4

Citalopram mean (SD) dosage (mg/day)

During first 2Ā weeks

20.2 (0.)

20.9 (4.2)

tā€‰=ā€‰āˆ’1.0, dfā€‰=ā€‰42, Pā€‰=ā€‰.3

During weeks 3 and 4

24.0 (6.6)

24.5 (7.3)

tā€‰=ā€‰āˆ’.2, dfā€‰=ā€‰42, Pā€‰=ā€‰.8

During second month

35.0 (7.4)

33.5 (7.4)

tā€‰=ā€‰āˆ’.6, dfā€‰=ā€‰40, Pā€‰=ā€‰.5

Hamilton Depression Rating Scale score

Baseline

21.4 (4.1)

22.4 (3.0)

tā€‰=ā€‰āˆ’.9, dfā€‰=ā€‰42, Pā€‰=ā€‰.3

Week 2

15.0 (5.6)

16.9 (6.0)

tā€‰=ā€‰1.0, dfā€‰=ā€‰42, Pā€‰=ā€‰.4

Week 4

11.2 (6.8)

11.9 (5.9)

tā€‰=ā€‰āˆ’.3, dfā€‰=ā€‰41, Pā€‰=ā€‰.7

Week 8

8.6 (5.2)

9.3 (6.3)

tā€‰=ā€‰āˆ’.3, dfā€‰=ā€‰41, Pā€‰=ā€‰.6

Decline of Hamilton Depression Rating Scale score (%)

60.0 (20.3

59.2 (26.9)

tā€‰=ā€‰āˆ’.1, dfā€‰=ā€‰41, Pā€‰=ā€‰.9

Mean (SD) of Beck Depression Inventory score

Baseline

23.9 (8.3)

22.8 (9.8)

tā€‰=ā€‰āˆ’.3, dfā€‰=ā€‰41, Pā€‰=ā€‰.6

Week 2

18.0 (11.1)

17.9 (9.8)

tā€‰=ā€‰.02, dfā€‰=ā€‰41, Pā€‰=ā€‰.9

Week 4

14.8 (10.8)

15.1 (10.4)

tā€‰=ā€‰.1, dfā€‰=ā€‰41, Pā€‰=ā€‰.9

Week 8

8.6 (10.7)

9.0 (9.6)

tā€‰=ā€‰āˆ’.1, dfā€‰=ā€‰41, Pā€‰=ā€‰.9

Mean (SD) decline of suicidal score

1.0 (0.9)

0.9 (0.9)

tā€‰=ā€‰āˆ’.3, dfā€‰=ā€‰37, Pā€‰=ā€‰.7

  1. Abbreviation: ECT electroconvulsive therapy.