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Table 1 SHINE two-sided P values for stopping for success or futility at each interim analysis

From: The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study

Information fraction SuccessPValue FutilityPValue
36% 0.003 0.949
50% 0.004 0.896
64% 0.008 0.652
78% 0.016 0.293
100% 0.043 0.043