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Table 1 Patient characteristics at baseline and at the end of the Syst-Eur 1 trial

From: How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2)

 

Baseline Syst-Eur 1

Baseline Syst-Eur 2

Characteristic

Placebo

Active

Placebo†

 

Active†

Number

1691

1825

1691

 

1825

Female sex

1121 (66.3%)

1219 (66.8%)

1121 (66.3%)

 

1219 (66.8%)

Age (years)

69.0 ± 6.0

69.0 ± 5.8

71.1 ± 6.4++

 

71.2 ± 6.3++

Sitting systolic blood pressure (mmHg)

173.4 ± 9.5

173.3 ± 9.4

160.4 ± 16.2++

***

151.0 ± 14.6++

Sitting diastolic blood pressure (mmHg)

85.6 ± 5.7

85.7 ± 5.7

83.4 ± 7.7++

***

79.6 ± 7.8++

Sitting heart rate (beats per minute)

72.8 ± 8.0

72.8 ± 7.9

72.5 ± 9.1

*

73.1 ± 8.9

Standing systolic blood pressure (mmHg)

168.3 ± 11.5

167.9 ± 11.9

157.6 ± 16.6++

***

148.2 ± 15.5++

Standing diastolic blood pressure (mmHg)

87.6 ± 7.6

87.6 ± 7.6

85.1 ± 9.2++

***

81.6 ± 8.9++

Body-mass index (kg/m2)

27.3 ± 4.0

27.3 ± 4.2

27.0 ± 4.0++

 

27.1 ± 4.2++

Total cholesterol (mmol/l)

6.0 ± 1.2

6.0 ± 1.2

5.9 ± 1.1++

 

5.8 ± 1.1++

High-density-lipoprotein cholesterol (mmol/l)

1.40 ± 0.46

1.42 ± 0.48

1.36 ± 0.40+

*

1.40 ± 0.47

History of stroke

18 (1.1%)

20 (1.1%)

39 (2.3%)++

 

34 (1.9%)++

History of myocardial infarction

61 (3.6%)

62 (3.4%)

73 (4.3%)++

**

71 (3.9%)++

Diabetes mellitus

170 (10.1%)

189 (10.4%)

205 (12.1%)++

 

235 (12.9%)++

Current smokers

106 (6.3%)

121 (6.6%)

71 (4.2%)++

 

86 (4.7%)++

Abstaining from alcohol

1227 (72.6%)

1311 (71.9%)

1324 (78.3%)++

 

1388 (76.1%)++

<1 unit alcohol per day

282 (16.7%)

337 (18.4%)

225 (13.3%)++

 

261 (14.3%)++

≥ 1 unit alcohol per day

181 (10.7%)

176 (9.7%)

142 (8.4%)++

 

175 (9.6%)

  1. Values are given as mean ± SD or number of patients (%). † Indicates patients formerly randomised to placebo and active treatment. Significance of between-group differences: *P < 0.05; **P < 0.01; ***P < 0.001. Significance of within-group changes: +P < 0.01; ++P < 0.001.