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Table 3 Summary of recent randomized exercise therapy and cardiac rehabilitation (CR) trials investigating the effects on long-term mortality

From: Cardiac rehabilitation: a comprehensive review

    

Follow-up

 
 

Cohort

Intervention

Comparison group

(years)

Relative risk reduction*

Hedback

305 men and women,

Multifactorial, 2 x per week

Nonrandomized reference

10

27% all-cause mortality

et al [21]

post-MI, < 65 years

exercise sessions, 3 months

with no CR

 

(P < 0.01)

     

24% cardiovascular mortality

     

(P <0.001)

     

33% nonfatal MI (P <0.001)

PRECOR

182 men post-MI,

Multifactorial, 3 x per week

Control (usual care,

2

7% absolute reduction in

Group [20]

< 65 years

exercise sessions; or

no intervention)

 

all-cause mortality† (P = 0.08)

  

counselling only, 6 weeks

   

Hamalainen

375 men and women,

Multifactorial, exercise

Randomized control group

15

4% all-cause mortality

et al [25]

post-MI, < 65 years

sessions, 3 years

  

(not significant)

     

18% cardiovascular mortality

     

P = 0.04)

     

43% sudden death

     

(P = 0.006)

NEHDP [26]

651 men, post-MI,

Exercise only, 2 years

Control (usual care,

19

No reported benefits

 

< 65 years

 

no intervention)

  
  1. MI, Myocardial infarction; NEHDP, The National Exercise and Heart Disease Project. * Relative risk reduction in favor of intervention. † No deaths occurred in CR intervention. results are based on comparison of CR intervention with counselling intervention and control (usual care, no intervention) combined.
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Trials

ISSN: 1745-6215