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Table 1 Myocardial infarctions identified by site investigators but not confirmed by the clinical events committee

From: Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study

  Eastern Europe Latin America North America Western Europe Overall
Clinical scenario (n = 24) (n = 8) (n = 57) (n = 78) (n = 167)
Enrolment myocardial infarction* 8 (33) 4 (50) 24 (42) 28 (36) 64 (38)
Ischemic event without infarction 7 (29) 0 (0) 8 (14) 19 (24) 34 (20)
Peri-death infarction 6 (25) 2 (25) 13 (23) 8 (10) 29 (17)
Percutaneous coronary intervention related 0 (0) 1 (12.5) 6 (11) 10 (13) 17 (10)
Coronary artery bypass surgery related 2 (8) 1 (12.5) 5 (9) 7 (9) 15 (9)
Miscellaneous 1 (4) 0 (0) 1 (2) 6 (8) 8 (5)
  1. Data presented as n (%). * Not an end-point event per protocol. Clinical evidence of ischemia without electrocardiography (ECG) or cardiac enzyme evidence of infarction. Infarction suspected at the time of death without supporting clinical, ECG, or cardiac enzyme data.