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Table 1 Epidemiological studies of the associated risk between dyslipidemia and venous thromboembolism (VTE)

From: The role of dyslipidemia and statins in venous thromboembolism

      

Prevalence

 
      

of lipid

Odds

  

Mean age

 

% cases

 

risk factor

ratio

 

No. cases/

of cases

VTE

with situational

 

among

(95% CI)

Study [reference]

controls

(years)

type

risk factors*

Serum lipid risk factor(s)

cases (%)

for VTE

Goldhaber et al [7]

280/112542

30–55

PE

55

Self-reported elevated TC

18

1.1 (0.7–1.5)

Kawasaki et al [8]

109/109

50

Leg DVT

34

TC > 5.7 mmol/L and TG > 1.7 mmol/L

23

5.1 (2.0–13.0)

     

TC > 5.7 mmol/L and TG ≤ 1.7 mmol/L

26

2.6 (1.2–5.3)

Nowak-Gottl et al [10]

186/186

5

Any VTE

60

Lp(a) > 30 mg/dL

42

7.2 (3.7–14.5)

von Depka et al [11]

685/266

34

Any VTE

21

Lp(a) > 10 mg/dL

40

1.6 (1.2–2.2)

     

Lp(a) > 20 mg/dL

25

2.2 (1.5–3.3)

     

Lp(a) > 30 mg/dL

20

3.2 (1.9–5.3)

  1. *Defined as either immobilization (i.e. trauma, surgery, or bedridden) or presence of an indwelling venous catheter at the site of thrombosis. DVT = deep vein thrombosis; Lp(a) = lipoprotein (a); PE = pulmonary embolism; TC = total cholesterol; TG = triglycerides; VTE = venous thromboembolism.
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