Table 2 Effect of ramipril on echocardiographic measurements of left ventricular mass and function in a substudy of HOPE
From: Dose response of ACE inhibitors: implications of the SECURE trial
Echocardiographic variable | Placebo | Ramipril 2.5 mg/day | Ramipril 10 mg/day |
|---|---|---|---|
Δ LVMI (g/m2) | 3.98 ± 25.23 | 4.15 ± 22.77 | -2.02 ± 27.12* |
Δ LVEF (%) | -2.02 ± 1.54 | -1.54 ± 8.94 | -0.17 ± 8.62†|
Δ LVEDV (ml) | 4.16 ± 30.89 | -0.43 ± 33.3 | -5.90 ± 35.17††|
Δ LVESV (ml) | 5.31 ± 20.49 | 2.90 ± 17.68 | -1.90 ± 18.71††|
New wall motion abnormalities | 31 | 30 | 23 |