Table 2 Allele frequencies of the prothrombin, factor V, MTHFR and MTRR polymorphisms among 129 women with VTE and 129 matched control individuals

From: Genetics University of Toronto Thrombophilia Study in Women (GUTTSI): genetic and other risk factors for venous thromboembolism in women

	Gene polymorphism
	Prothrombin		Factor V		MTHFR		MTHFR		MTHFR		MTRR
	G20210A		G1691A		C677T		A1298C		T1317C		A66G
Allele	Cases	Controls	Cases	Controls	Cases	Controls	Cases	Controls	Cases	Controls	Cases	Controls
-/-	117	126	108	124	49	72	68	69	122	123	25	29
+/-	11	3	19	5	61	44	49	49	6	5	62	65
+/+	1	0	2	0	19	13	12	11	1	1	42	35
Frequency	0.050	0.012	0.089	0.019	0.384	0.271	0.283	0.275	0.031	0.027	0.566	0.523
Fisher's exact test P value	0.02		0.0007		0.008		0.92		1.0		0.4

-/-, Wildtype; +/-, heterozygote; +/+, homozygote.

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ISSN: 1745-6215

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